From First Principles is a fast, funny, and rigorous breakdown of the biggest science stories of the week, hosted by Lester Nare and physicist Krishna Choudhary, PhD. We go past headlines into the actual mechanics: what happened, why it matters, and what everyone’s missing.
Expect physics, space, AI, energy, biotech, and the occasional “wait… is that real?” story. If you’re curious, skeptical, and you like learning in public — you’re in the right place.
From First Principles unpacks the 2026 Nobel Prize in Chemistry awarded to Henri B. Kagan and Kenso Soai for their work on nonlinear effects and autocatalysis in asymmetric organic synthesis. Hosts Lester Nare and Krishna Choudhary build from foundational concepts: chirality (molecular mirror-image handedness),…
Worth it if you want to understand the 2026 Nobel Prize in Chemistry, are curious about why life is left-handed, or appreciate rigorous science explanation that doesn't talk down to listeners.
From First Principles Episode 62 celebrates the 2026 Nobel Prize in Physics awarded to Francis Halzen for his work on IceCube and the discovery of high-energy cosmic neutrinos. Hosts Lester Nare and Krishna Choudhary build a comprehensive narrative from first principles, starting with what neutrinos are (elusive…
Worth it if you want to understand how we detect cosmic neutrinos, appreciate the engineering behind major physics discoveries, or follow current Nobel Prize science with real depth.
From First Principles Episode 61 traces the 2026 Nobel Prize in Medicine, awarded for optogenetics—a technique that uses light-sensitive proteins to control neural activity with precision. Hosts Lester Nare and Krishna Choudhary build the story from first principles, beginning with the fundamental neuroscience…
Worth it if you want to understand a major neuroscience breakthrough, appreciate how fundamental discoveries become tools, or need to know what the 2026 Medicine Nobel actually celebrates.
